Chronopharmacology of immunosuppressants.

Annual Review of Chronopharmacology

The f r a c t i o n a l d i s t r i b u t i o n o f l y m p h o c y t e subsets was d e t e r m i n e d i n t h r e e m a l e s u b j e c t s . I t s c o n t r i b u t i o n t o t h e c i r c a d i a n v a r i a t i o n i n t h e exp r ess i on o f ß2~adrenoceptor s i t e s on pe r iphera l m o n o n u c l e a r l e u c o c y t e s ( M N L ) was c a l c u l a t e d t o be 92 .7 -107 .3 % o f t ...

Annual Review of Chronopharmacology

Chronopharmacology of Anti-Convulsive Therapy

Approximately one-third of patients with epilepsy continue to have seizures despite antiepileptic therapy. Many seizures occur in diurnal, sleep/wake, circadian, or even monthly patterns. The relationship between biomarkers and state changes is still being investigated, but early results suggest that some of these patterns may be related to endogenous circadian patterns whereas others may be re...

Annual Rev Iew of Chronopharmacology

Concept of Chronopharmacology in Ayurveda

Rhythmicity is a ubiquitous phenomenon. Rhythmic temporal patterns are considered and important factor in therapeutics as effective treatments should work in conjunction with body's clocks. Te concept of chronobiology is well evidenced by the cyclic alterations of dosas in the body. The Ayurvedic way of living as well as healing has been developed keeping in mind these biological clocks so as t...